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Live Attenuated Vaccines

Live Attenuated Vaccines

Live Attenuated Vaccines: Benefits, Risks & Examples

Live Attenuated Vaccines: Benefits, Risks & Examples

Live attenuated vaccines are one of the most effective types of vaccines used to protect against infectious diseases. These vaccines contain a weakened form of the virus or bacteria, which is strong enough to trigger an immune response but not potent enough to cause illness in healthy individuals.

Live attenuated vs killed vaccine design

How Do they Work?

When a live attenuated vaccine is administered, the weakened pathogen replicates slowly in the body. So, This mimics a natural infection and stimulates a robust and long-lasting immune response. The body produces antibodies and memory cells, which help to fight off the actual infection if exposed in the future.

Benefits of Live Attenuated Vaccines

  • Long-lasting immunity: Often provides lifelong protection with just one or two doses.
  • Strong immune response: Mimics natural infection closely.
  • Effective against various diseases: Used in vaccines for measles, mumps, rubella, and more.

Risks and Considerations

While generally safe, they are not suitable for everyone. Individuals with weakened immune systems, pregnant women, or those with certain medical conditions should avoid them unless advised otherwise by a healthcare professional.

Also, Possible side effects may include mild fever, rash, or soreness at the injection site. Serious side effects are rare.

Examples of Live Attenuated Vaccines

  • Measles, Mumps, and Rubella (MMR) vaccine
  • Varicella (chickenpox) vaccine
  • Rotavirus vaccine
  • Oral Polio Vaccine (OPV)
  • Yellow Fever vaccine
  • Also, Intranasal Influenza (FluMist) vaccine
Intranasal live attenuated SARS-CoV-2 vaccine

Who Should Get Live Vaccines?

Most healthy children and adults can safely receive live attenuated vaccines. Also, They are often part of routine childhood immunization programs. However, always consult your healthcare provider to determine if they are appropriate for you or your child.

Conclusion

They play a vital role in preventing infectious diseases and controlling outbreaks.Therefore, Understanding how they work, their benefits, and potential risks empowers you to make informed health decisions. For more information, you can join OPRA exam preparation course.

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