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Drug for Parkinson’s Disease: Insights, Treatment, and Advancements

Introduction

Parkinson’s disease, a chronic and progressive movement disorder, affects millions worldwide. First described by James Parkinson in 1817, its pathology involves changes in melanin-containing nerve cells in the brainstem. While there is no cure, medications play a crucial role in managing symptoms and improving patients’ quality of life.

Understanding Parkinson’s Medications

Several drug classes are used to rebalance dopamine levels and alleviate symptoms:

  1. Levodopa (Carbidopa/Levodopa):

  2. Dopamine Agonists (Ropinirole, Pramipexole):

  3. MAO-B Inhibitors (Rasagiline, Selegiline):

  4. COMT Inhibitors (Entacapone, Tolcapone):

  5. Amantadine:

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